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Current treatment options
Early treatment focuses on stabilizing the spine, protecting the remaining nerve tissue and preventing complications. In the longer term, rehabilitation (physiotherapy, occupational therapy and assistive technology) remains the foundation of care and recovery.
There is currently no treatment that reliably repairs a damaged spinal cord. Cell-based therapies are one of several areas of active research that aim to improve recovery beyond what rehabilitation alone can achieve.
How mesenchymal stem cells are being studied in spinal cord injury
Mesenchymal stem cells (MSCs) are not expected to replace damaged nerve cells directly. Research suggests that they act mainly through the signals they release: they may reduce inflammation, protect surviving tissue and support an environment in which nerve fibers can recover.
Published reviews of clinical studies report improvements in sensory scores and, in some studies, in motor function and daily activities after MSC treatment. Umbilical cord-derived MSCs and delivery into the spinal fluid (intrathecal administration) are among the most studied approaches.
These results come largely from small studies, many without a control group, and outcomes vary considerably between patients. Researchers agree that larger, well-controlled trials are needed. MSC therapy for spinal cord injury is therefore an emerging approach, not a cure.
In Japan, a stem cell product for spinal cord injury received a conditional, time-limited approval in 2018 while its effectiveness continues to be evaluated, which reflects both the interest in this field and the caution of regulators.
Stem cell therapy for spinal cord injury at Istanbul Stemcell
At Istanbul Stemcell, treatment uses Wharton’s jelly-derived mesenchymal stem cells (MSCs) from donated umbilical cord tissue.
Every treatment plan starts with an individual medical assessment. Our specialists review your MRI scans, medical history and current level of function before advising whether treatment may be appropriate for you.
As part of your personal treatment plan, your doctor explains how the cells are given, how many sessions are planned, how long you would stay in Istanbul and how follow-up is arranged.
Stem cell therapy is intended to complement ongoing rehabilitation, not to replace it. Continuing physiotherapy after treatment is an important part of any plan.
What you can expect
Share your medical information: send us your MRI reports, discharge letters and a short description of your current function.
Specialist review: our medical team assesses whether treatment may be suitable and explains realistic expectations.
Personal treatment plan: if treatment is appropriate, you receive a plan covering the procedure, your stay and follow-up.
Treatment and follow-up: your plan describes the follow-up after treatment, and our team remains available for your questions once you are home.
Frequently Asked Questions
Can stem cell therapy cure a spinal cord injury?
No. Current evidence does not show that any stem cell therapy can cure a spinal cord injury. Some studies report improvements in sensation and function, but results vary and are not guaranteed.
Who may be a candidate?
Suitability depends on the level and type of injury, the time since the injury, your general health and your goals. A specialist review of your medical records is needed before any recommendation.
Is the treatment safe?
In published studies, MSC treatments have generally been reported as well tolerated. Possible side effects include temporary fever, headache and discomfort at the injection site, and injections into the spinal fluid can cause headache. Your doctor will explain the risks that apply to you before any treatment.
Do I need to continue rehabilitation?
Yes. Rehabilitation remains the foundation of recovery after a spinal cord injury, and continuing physiotherapy is recommended alongside any cell-based treatment.
Which documents should I send?
Recent MRI scans or reports of the spine, hospital discharge letters, a list of your medications and a short description of your current movement, sensation and daily activities.
Medical references
This page provides general information and does not replace a consultation with a doctor.
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